Diphenhydramine HCI 25 mg - 100 Tablets Review

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(More customer reviews)
Generic medications such as Diphenhydramine" are equally effective as the "name-brand" drugs such as Benadryl. Diphenhydramine is a medication that suppresses histamine release from cells, thus it is labelled as an "anti-histamine". Histamine is the compound in the body that produces all the symptoms of allergies, such as itching, swelling, redness, rash, hives, etc.
A "capsule" dose of Diphenhydramine is 25 mg, with the usual adult dose being 1-2 pills. This medication used to be a prescription product but became an over-the-counter medication in the 1990's. It is very effective in relieving allergy symptoms. The major side-effect of Diphenhydramine is drowsiness, which some manufacturers use to their advantage, packaging this medication as a sleeping aid, and a very effective one at that.
One precaution, don't mix this medication with any other depressants, such as alcohol, anti-anxiety agents, barbiturates, etc. The combined effect will produce profound sedation. In men, diphenhydramine can cause a prostate urinary retention problem.
Use diphenhydramine for allergy relief or as a sleeping pill - both uses work very well. I first used Diphenhydramine for relief of hives and it was very effective. If you are mentally and physically tired after taking this medication for an allergy, then switch to the over-the-counter Claritin, which has no drowsiness. It is much more expensive than Diphenhydramine, but the non-drowsy formula is a real benefit.
Hope this helps.
Jim "Koendog" Koenig

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Advil PM-Nighttime Pain Reliever and Sleep-Aid, 180ct Review

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(More customer reviews)I use this product for restless leg and it works wonders. If I take it about 30 minutes before going to bed, my legs quit hurting and I can quickly drop off to sleep. Restless leg isn't exactly painful, but it can be one of the most annoying things on earth. I use Advil PM a couple times a month and it really works for me.

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Unisom SleepGels, Maximimum Strength Nighttime Sleep Aid, Softgels 32 ea Review

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(More customer reviews)Like virtually all sleeping pills on the market, this one uses the active ingredient in Benadryl - diphenhydramine. Diphenhydramine is a sedating antihistamine. The sedation from 50 mg of diphenhydramine will cause you to become drowsy and sleepy, and will likely keep you this way for about 8-12 hours. Thus, not only will you likely sleep the night through, but you will have a groggy sleep hangover the next day until about noon.
Since this is an antihistamine, you will likely experience other mild side-effects, such as imbalance, urinary retention, and mild dry mouth. The urinary retention is of particular concern in men with prostate or bladder problems. The side effects are transient and wear off as the medication is metabolized and excreted from the body.
Benadryl (diphenhydramine) is not habit-forming or addictive in a physical way. It has the potential for psychological addiction. Thus, it is best used as an occasional aid for sleeplessness, not an every-night event
konedog

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Member's Mark Maximum Strength Sleep Aid Review

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(More customer reviews)This product is relatively cheap and will work as advertized. I like it better than the more expensive brand names, such as Tylenol PM, or others that have the exact same active ingredient.
Like virtually all sleeping pills on the market, this one uses the active ingredient in Benadryl - diphenhydramine. Diphenhydramine is a sedating antihistamine. The sedation from 50 mg of diphenhydramine will cause you to become drowsy and sleepy, and will likely keep you this way for about 8-12 hours. Thus, not only will you likely sleep the night through, but you will have a groggy sleep hangover the next day until about noon.
Since this is an antihistamine, you will likely experience other mild side-effects, such as imbalance, urinary retention, and mild dry mouth. The urinary retention is of particular concern in men with prostate or bladder problems. The side effects are transient and wear off as the medication is metabolized and excreted from the body.
Benadryl (diphenhydramine) is not habit-forming or addictive in a physical way. It has the potential for psychological addiction. Thus, it is best used as an occasional aid for sleeplessness, not an every-night event.
Jim Konedog Koenig (dentist)

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Nytol Nighttime Sleep-Aid, Caplets - 32 ea Review

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(More customer reviews)If you keep the Brand name antihystamine on hand, this is better. It works faster. It's not always more costly depending on where you buy it. Amazon has very inexpensive pricing options on this, and I couldn'd find it at my local pharmacy.
The other review is extremely informative.

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Kirkland Signature Nighttime Sleep Aid (Doxylamine Succinate 25 mg), 96-Count Tablets (Pack of 2) Review

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(More customer reviews)I used to have a very random schedule that caused me to have trouble sleeping. I originally bought these hoping that they would help me fall asleep quickly, especially in situations where I wasn't super tired, but still wanted to get a full 8 hours of sleep.
Unfortunately, for me at least, these don't really cause me to fall asleep much faster. What they do is keep me from getting up after four hours and not being able to go back to sleep. If I take these, I end up sleeping for at least 8 hours, and still feeling like I could go back to bed.
Now I only use these if I'm trying to get back to a normal sleep schedule by going to bed early and getting a full nights sleep. They work well for that, but I have to make sure I'm going to be able to sleep the full night, because I'll be zonked out otherwise.

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Diphenhydramine HCl 25 Mg Allergy Medicine and Antihistamine Compare to Active Ingredient of Benadryl® Allergy Generic - 400 Tablets Review

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(More customer reviews)Diphenhydramine is an antihistamine. It is used to block histamine release in the body. Histamine causes all manner of allergy symptoms: stuffy or runny nose, sinus inflammation, scratchy throat, itching, and hives.
Diphenhydramine is the ingredient in Benadryl, although Benadryl will cost much more than diphenydramine, since Benadryl is a brand-name drug. It is important to realize that both forms are equally equivalent in efficacy. Therefore, it makes sense to purchase the generic equivalent.
A major side effect of diphenhydramine is sedation/drowsiness. It will definately make you tired and sleepy. However, this side effect can be used as an advantage, as the medication can also be marketed as a sleeping aid. It will help you fall asleep faster and generally acts all night long. In fact, many people report a "hangover" morning effect from taking diphenhydramine the night before.
Thus, diphenhydramine has two main uses: that as an allergy medication and as a sleeping aid. Companies often add diphenhydramine to their analgesic products, such as Tylenol, to give both pain relief and a sleeping aid (Tylenol PM).
Diphenhydramine has other troubling side-effects that bear mentioning. First, is should not be used in those with narrow-angle glaucoma, or anyone with stomach problems, such as continual stomach upset or ulcers of the stomach. Second, diphenhydramine can cause a retention of urine, especially in those that have an enlarged prostate. Anyone with prostate problems should avoid diphenhydramine like the plaque. Don't take diphenhydramine with any other depressants, as the effects are additive. The same holds true for alcohol; don't take both at the same time.
The usual adult dosage is 25-50 mg, 3-4 times a day. Use the lowest effective dose to treat your symptoms. Pregnant women should avoid any antihistamines, as the medication has been known to cause birth defects.
While this is a great medication for allergies, there are better, newer antihistamines that do not produce the drowsiness that diphenhydramine does. (check out Claritin as a better, but more costly substitute).
Jim "Konedog" Koenig

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